01 - Pat chicken breasts dry with paper towels. Season both sides generously with 1 teaspoon salt and 1/2 teaspoon black pepper, pressing seasoning into the meat.
02 - Whisk together buttermilk, hot sauce, chopped jalapeños, and minced garlic in a large bowl until thoroughly combined.
03 - Submerge seasoned chicken breasts in the marinade, ensuring complete coverage. Cover and refrigerate for at least 1 hour, or up to overnight for maximum flavor penetration.
04 - Combine flour, cornmeal, smoked paprika, cayenne pepper, garlic powder, onion powder, salt, and pepper in a shallow dish. Whisk to distribute spices evenly.
05 - Remove chicken from marinade, allowing excess liquid to drip off. Dredge each piece in the breading mixture, pressing firmly to adhere the coating. Place breaded chicken on a wire rack.
06 - Pour vegetable oil into a deep skillet or Dutch oven to a depth of 2 inches. Heat to 350°F, maintaining temperature throughout frying.
07 - Fry chicken breasts in batches without overcrowding. Cook for 6-8 minutes per side until golden brown and crispy. Verify internal temperature reaches 165°F for doneness.
08 - Transfer cooked chicken to a wire rack or paper towels to drain. Let rest for 5 minutes before serving to retain juices.